What Are SARMs? The Comprehensive Guide to SARMs Types, Effects, Safety, and Legality
January 27th 2026
In today’s fitness and bodybuilding community, many people are always on the lookout for new and innovative ways to improve their physique and performance.
When it comes to enhancing muscle mass, improving strength, and boosting general performance, anabolic steroids have been the go-to option for many individuals. However, the drawbacks and potential health risks associated with steroids have led to the search for alternative solutions. This is where SARMs products come to take place.
In this guide, you will dive into the world of SARMs, understanding what they are, how they work, and their effects on the body, Moreover, covering their safety profile, their comparison to steroids, the reasons behind their illegality, and explore the best safe alternatives to SARMs.
Brutal Force LIGABULK
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Brutal Force LIGABULK
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Best SARMs Alternatives
Quick Decision Guide: Our Top-Rated Ostarine Alternative (DBULK)
Criteria | Brutal Force LIGABULK | Brutal Force ANDALEAN |
|---|---|---|
Overall Rating | 91%
Fill Counter
| 90%
Fill Counter
|
Main Benefits | Builds high quality muscle, supports strength increases, significantly decreases recovery time. Safe, natural and legal. | Cuts fat whilst increasing energy and preserving lean muscle. Supports increases in strength. Safe, natural and legal. |
Scientific Backing | Strong | Strong |
Formula Complexity | High, scientifically proven approach | High, scientifically proven approach |
Brand Reputation Concerns | None, praised for efficacy | None, praised for efficacy |
Commitment Time For Results | Weeks, consistent use recommended for best results | Several weeks, consistent use required for best results |
User Reviews | Positive reviews with many users reporting noticeable increases in size and strength | Predominantly positive reviews with many users reporting noticeable increases in size and strength |
Formula Complexity | Clear information on dosages | Clear information on dosages |
Potential Side Effects | None, well-tolerated | None, well-tolerated |
Customer Support & Returns Policy | Excellent, with a 100 day money-back guarantee | Excellent, with a 100 day money-back guarantee |
Product Availability | Available through the official site only | Available through the official site only |
Additional Benefits | Increases energy and supports overall motivation | Reduced recovery time |
Cost | Mid-range | Mid-range |
Serving Size | 3 capsules | 3 capsules |
Servings Per Container | 30 | 30 |
Price |
What Are SARMs?
SARMS, short for Selective Androgen Receptor Modulators, are a class of compounds that bind to androgen receptors in the body.
Unlike anabolic steroids, which affect multiple tissues, SARMs have a selective impact, targeting specific tissues, such as muscle and bone, while minimizing side effects on other organs.
This selectivity makes SARMs products an attractive option for many athletes and fitness enthusiasts.
How Do SARMs Work?
They work by selectively targeting and binding to androgen receptors in the body. Unlike anabolic steroids, SARMs are designed to only affect specific tissues, like muscle and bone.
This targeted approach can help to increase muscle mass and bone density, without the negative side effects associated with traditional steroids. The exact mechanism of action for SARMs research suggests that they may work by stimulating protein synthesis, increasing nitrogen retention, and increasing bone mineral density.
While SARMs have shown promise in clinical trials and in anecdotal reports, more researchers are running to fully understand their long-term effects on the body.
What do SARMs do to the body?
- Stimulates muscle growth
SARMs activate anabolic pathways in muscle cells, leading to increased protein synthesis and muscle hypertrophy.
This can result in significant gains in lean muscle mass and increased bone density, making SARMs popular among bodybuilders and athletes aiming to improve their physiques.
- Increased strength
SARMS have the potential to boost strength levels, allowing individuals to lift heavier weights and perform better during intense workouts.
This can be particularly beneficial for athletes involved in strength-based sports or individuals looking to break through performance plateaus.
- Raise metabolic rate
In addition to promoting muscle growth, SARMs have shown promising results in increasing fat loss. By activating the androgen receptors in adipose tissue, these compounds can accelerate the breakdown of stored fat and enhance metabolic activity. Furthermore, SARMs help preserve muscle mass during calorie-restricted periods, which is crucial for maintaining a toned and defined physique.
- Increased Bone Density
SARMs are known for their ability to increase bone density in individuals who are at risk of developing osteoporosis or other bone-related illnesses. Bone health is a critical aspect of overall health, particularly as we age. Unfortunately, many individuals experience a gradual loss of bone tissue as they grow older, which can lead to an increased risk of fractures and other complications.
SARMs have been shown to be an effective tool in combating this issue. SARMs work by binding to androgen receptors in the body, which in turn stimulates the growth of bone tissue. This increased bone density not only helps to prevent fractures and other bone-related injuries but can also improve overall mobility and balance.
- Improves endurance
Certain SARMs have demonstrated the ability to enhance endurance levels, enabling athletes to push their limits and extend their workouts. This can be advantageous for endurance athletes, such as long-distance runners or cyclists, who require sustained performance over extended periods.
Why do people use SARMs?
Athletes, both professional and recreational, seek SARMs for their potential to improve athletic performance. These compounds can enhance strength, power, and speed, allowing athletes to push their physical limits. SARMs have been associated with increased stamina, which can be advantageous in activities requiring prolonged exertion.
Moreover, SARMs can contribute to muscle definition and vascularity, providing athletes with a more aesthetically pleasing appearance. These effects make SARMs an attractive option for individuals participating in sports or competitions where physical performance and appearance are key factors.
Another significant benefit of SARMs is their potential to accelerate injury recovery. These compounds have been found to possess tissue-regenerative properties, promoting the healing of damaged muscles, tendons, and ligaments. Additionally, SARMs exhibit anti-inflammatory effects, which can aid in reducing pain and inflammation associated with injuries.
For athletes and fitness enthusiasts, faster recovery means less downtime and the ability to return to training or competition sooner. This aspect makes SARMs an appealing option for those looking to optimize their recovery process and get back to peak performance levels swiftly.
SARMs vs.Traditional Steroids, What are the differences?
SARMs and traditional steroids are two categories of performance-enhancing substances that are often compared. While both are used to enhance muscle growth and athletic performance, there are significant differences between them in terms of their mechanism of action, selectivity, side effects, and legal status.
- Benefits of SARMs over Steroids
First and foremost, SARMs are selective in their action, meaning they target specific androgen receptors in the body, such as those found in muscle tissue, while minimizing or even eliminating the potential side effects associated with traditional steroids. This makes them a safer alternative for individuals looking to improve their physical performance without experiencing the negative side effects of anabolic steroids.
Another key difference is that SARMs do not convert to estrogen in the body, unlike traditional steroids, which can cause a range of undesirable side effects, such as water retention, breast enlargement in men, and decreased libido. This is because SARMs selectively bind to androgen receptors, without affecting the body’s natural estrogen levels.
Overall, the choice between SARMs and traditional steroids ultimately depends on an individual’s specific fitness goals and concerns. While traditional steroids may offer more potent anabolic effects, they come with a higher risk of potential side effects, while SARMs offer a safer and more selective alternative. It is important to understand the potential benefits and risks associated with both options and make an informed decision.
Common Types of SARMs
- Ostarine
Also known as MK-2866. Ostarine MK 2866 has been shown to have potent anabolic effects, leading to increased lean muscle mass and improved athletic performance. It has also been shown to improve bone density, making it a promising option for those dealing with osteoporosis or other bone-related conditions.
- Ligandrol
Or LGD-4033. Ligandrol was originally developed for medical purposes to treat conditions such as muscle wastage and osteoporosis. However, due to its anabolic effects, Ligandrol has become a popular option among bodybuilders, fitness enthusiasts, and athletes looking to enhance their physical performance and gain lean body mass.
Ligandrol SARM also has the potential to improve bone mineral density, which is especially important for those suffering from osteoporosis or other bone-related conditions. This can result in improved joint health and overall physical well-being.
- Andarine
Andarine, or S4. Unlike testosterone and other anabolic steroids, Andarine does not convert to estrogen, which can lead to unwanted side effects such as water retention and gynecomastia. Instead, it promotes the development of lean muscle mass and improved bone density, making it an attractive option for those who may be sensitive to the estrogenic effects of other anabolic steroids.
- Cardarine
Cardarine, also known as GW-501516, is a popular selective androgen receptor modulator that has gained a lot of attention in recent years due to its potential health benefits. This investigational drug is not approved for human consumption, but it is commonly used by fitness enthusiasts who are looking for a safer alternative to anabolic steroids.
It is also known for its ability to increase metabolic activity, which can lead to faster fat loss and improved cardiovascular health. By activating the PPAR-delta receptors in the body, Cardarine can increase the rate at which the body burns fat for energy, even during periods of rest. This can lead to improved body composition and a reduction in overall body fat, making it an excellent option for those who are looking to improve their overall health and wellness.
- RAD140
RAD 140, also known as Testolone, is a SARM that has shown promise in treating muscle-wasting conditions such as sarcopenia and cachexia. Research has also suggested that RAD 140 may have neuroprotective effects, making it a promising option for those dealing with conditions such as Alzheimer’s disease or Parkinson’s disease.
- YK-11
YK-11 is categorized as a SARM supplement due to its selective binding with healthy androgen receptors in the muscle, despite its steroid-like properties and benefits.
- Ibutamoren
Ibutamoren, commonly known as MK-677 is popular among fitness enthusiasts for its ability to boost human growth hormone (HGH) levels in the body. The compound works by binding to the ghrelin receptor, which stimulates the production of HGH and insulin-like growth factor 1 (IGF-1). This results in several potential benefits for users, including increased lean muscle mass, improved bone density, and enhanced fat burning.
One of the key benefits of Ibutamoren is its ability to support muscle growth and development through its anabolic effects. By boosting HGH and IGF-1 levels, Ibutamoren promotes protein synthesis in the body, which can lead to an increase in lean muscle mass over time. This makes it a popular choice for bodybuilders and fitness enthusiasts looking to build muscle and improve their physical performance.
- S-23
S-23 has been shown to have a positive effect on bone tissue and bone mineral density, making it a potential treatment for conditions such as osteoporosis and other bone-related diseases. This is due to its ability to stimulate the production of new bone cells, leading to stronger bones and a reduced risk of fractures.
- SR9009
SR9009, also known as Stenabolic. It has the ability to activate a protein called REV-ERB, which is responsible for controlling the body’s internal clock. By activating this protein, SR9009 can help optimize the body’s metabolic rate and energy usage, leading to increased endurance and a reduction in body fat.
Another benefit of SR9009 is that it can help improve sleep quality, which is crucial for athletes and fitness enthusiasts who need to recover properly after intense workouts. By regulating the body’s circadian rhythm, SR9009 can help athletes get a better night’s sleep leading to better muscle recovery.
How are SARMs used?
SARMs are typically taken orally, either in liquid or capsule form. Dosage recommendations vary depending on the specific compound, goals, and individual factors. It’s essential to follow proper dosage guidelines and consult with a healthcare professional or knowledgeable expert before starting a SARMs regimen.
Users often employ cycles and stacking strategies to optimize the benefits of SARMs. Cycling involves using it for a designated period, followed by a break to allow the body to recover and avoid potential side effects.
Stacking refers to combining different SARMs to synergistically enhance their effects. However, it’s important to note that the long-term effects of SARMs and optimal usage protocols are still subjects of ongoing research.
SARMs Unwanted Side Effects
- Hormonal imbalances
One of the primary concerns with SARMS use is the potential disruption of hormonal balance. SARMS can suppress natural testosterone production, leading to a decrease in endogenous hormone levels. This hormonal imbalance can result in symptoms such as reduced libido and fatigue.
It is important to monitor hormone levels closely and consider post-cycle therapy to restore hormonal balance after SARMS use.
- Changes in cholesterol levels
While SARMs are designed to have a more selective impact than traditional steroids, some studies suggest that certain SARMs may affect lipid profiles and cardiovascular health. They can alter cholesterol levels, potentially leading to an imbalance between HDL (good cholesterol) and LDL (bad cholesterol). This imbalance can increase the risk of cardiovascular problems such as heart disease.
Regular cardiovascular check-ups and monitoring of lipid profiles are essential for individuals using SARMS.
- Cause of acne
SARMS have been reported to cause acne and other skin-related problems in some individuals. Androgen receptors play a role in sebum production, and the modulation of these receptors by SARMS can lead to increased sebum production, potentially resulting in acne breakouts.
It is important to maintain good skin care practices and seek professional advice if acne becomes severe or persistent.
- Mood swings
Mood swings can manifest as sudden and intense shifts in mood, ranging from feelings of euphoria and energy to irritability, sadness, or anger. Several factors may contribute to mood swings associated with SARMS use:
- Hormonal Changes
As mentioned earlier, SARMS can suppress natural testosterone production, leading to hormonal imbalances. Testosterone plays a crucial role in mood regulation, and a decrease in testosterone levels can impact emotional well-being. - Estrogen Conversion
Some SARMS have the potential to convert to estrogen in the body. Elevated estrogen levels can also contribute to mood swings, as estrogen influences neurotransmitter activity in the brain. - Psychological Factors
It’s important to note that mood swings can be influenced by psychological factors as well. The anticipation of results, body image concerns, or the pressure to achieve certain performance goals can contribute to emotional fluctuations, irrespective of SARMS use.
Are SARMs legal to use?
Selective Androgen Receptor Modulators have been banned by the World Anti-Doping Agency (WADA) since 2008. They are classified as anabolic agents, which puts them in the same category as steroids and other drugs that can be used for performance-enhancing purposes.
Despite their legal status in some countries, SARMs are still largely unregulated and many products may contain unlisted substances or contaminants. For this reason, it is important to ensure that any product you purchase is from a trusted source with reliable third-party testing of batch quality and purity. Additionally, the long-term safety of SARMs.
On account of this, Brutal Force took the vital step and provided the athletes with safe and legal alternatives consisting of natural ingredients.
Those products are specially manufactured in the United States of America in fully equipped factories.
Those factories have obtained U.S. Food and Drug Administration (FDA) approval, to meet quality standards and comply with other technical requirements.
Overall Recommendation
Brutal Force LIGABULK
Overall Rating
Brutal Force LIGABULK
Overall Rating
Best SARMs Alternative
Conclusion
While some SARMs may be safer than anabolic steroids, they are not entirely without risks. Anyone considering using them should consult with their doctor and carefully research the compound they plan to use. Additionally, individuals should be aware of the potential for adverse side effects and take steps to mitigate their risks, such as using SARMs in moderation and using reputable, high-quality products from reputable manufacturers.
For those seeking a legal and safe alternative to ostarine, consider LIGABULK from Brutal Force. LIGABULK mimics the muscle-building benefits of the popular SARM, but with all-natural ingredients, it has none of the nasty side effects.
Our recommended safe and legal alternative to Andarine S-4 is ANDALEAN, which I've found to be highly effective during cutting cycles, particularly in supporting fat loss whilst protecting lean muscle.
References
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Miner JN, Chang W, Chapman MS, et al. An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate. Endocrinology. 2007;148(1):363–373. https://doi.org/10.1210/en.2006-0793
Ostrowski J, Kuhns JE, Lupisella JA, et al. Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in rats. Endocrinology. 2007;148(1):4–12. https://doi.org/10.1210/en.2006-0843
Gao W, Dalton JT. Ockham’s razor and selective androgen receptor modulators (SARMs): are we overlooking the role of 5α-reductase? Mol Interv. 2007;7(1):10–13. https://doi.org/10.1124/mi.7.1.3
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Mohler ML, Bohl CE, Jones A, et al. Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. J Med Chem. 2009;52(12):3597–3617. https://doi.org/10.1021/jm900280m
Schmidt A, Kimmel DB, Bai C, et al. Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy… J Biol Chem. 2010;285:17054–17064. https://doi.org/10.1074/jbc.M109.099002
Jones A, Hwang DJ, Duke CB, et al. Nonsteroidal selective androgen receptor modulators enhance female sexual motivation. J Pharmacol Exp Ther. 2010;334:439–448. https://doi.org/10.1124/jpet.110.168880
Basaria S, Collins L, Dillon EL, et al. The safety, pharmacokinetics, and effects of LGD-4033… in healthy young men. J Gerontol A Biol Sci Med Sci. 2013;68(1):87–95. https://doi.org/10.1093/gerona/gls078
Nejishima H, Yamamoto N, Suzuki M, et al. Anti-androgenic effects of S-40542… for the treatment of benign prostatic hyperplasia. Prostate. 2012;72:1580–1587. https://doi.org/10.1002/pros.22511
Akita K, Harada K, Ichihara J, et al. A novel selective androgen receptor modulator, NEP28, is efficacious in muscle and brain without serious side effects on prostate. Eur J Pharmacol. 2013;720:107–114. https://doi.org/10.1016/j.ejphar.2013.10.042
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Ponnusamy S, Sullivan RD, Thiyagarajan T, et al. Tissue Selective Androgen Receptor Modulators (SARMs) Increase Pelvic Floor Muscle Mass in Ovariectomized Mice. J Cell Biochem. 2017;118:640–646. https://doi.org/10.1002/jcb.25751
Narayanan R, Coss CC, Dalton JT. Development of selective androgen receptor modulators (SARMs). Mol Cell Endocrinol. 2018;465:134–142. https://doi.org/10.1016/j.mce.2017.06.013
Kawanami T, Tanaka T, Hamaguchi Y, et al. Selective Androgen Receptor Modulator S42 Suppresses Prostate Cancer Cell Proliferation. Endocrinology. 2018;159:1774–1792. https://doi.org/10.1210/en.2018-00099
Yatsu T, Kusakabe T, Kato K, et al. Selective Androgen Receptor Modulator, YK11, Up-Regulates Osteoblastic Proliferation and Differentiation… Biol Pharm Bull. 2018;41:394–398. https://doi.org/10.1248/bpb.b17-00748
Hoffmann DB, Komrakova M, Pflug S, et al. Evaluation of ostarine as a selective androgen receptor modulator in a rat model of postmenopausal osteoporosis. J Bone Miner Metab. 2019;37:243–255. https://doi.org/10.1007/s00774-018-0929-9
Muta Y, Tanaka T, Hamaguchi Y, et al. Selective androgen receptor modulator, S42 has anabolic and anti-catabolic effects on cultured myotubes. Biochem Biophys Rep. 2019;17:177–181. https://doi.org/10.1016/j.bbrep.2019.01.006
Dobs AS, Boccia RV, Croot CC, et al. Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial. Lancet Oncol. 2013. https://doi.org/10.1016/S1470-2045(13)70055-X
Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004–2010. https://doi.org/10.1001/jama.2017.13844
Leaney AE, Beck P, Morris M, et al. Analysis of supplements available to UK consumers purporting to contain selective androgen receptor modulators. Drug Test Anal. 2021;13:1773–1783. https://doi.org/10.1002/dta.2908
Bedi H, Hammond C, Sanders D, Yang HM, Yoshida EM. Drug-induced liver injury from enobosarm (Ostarine), a selective androgen receptor modulator. ACG Case Rep J. 2021;8. https://doi.org/10.14309/crj.0000000000000518
Barbara M, Dhingra S, Mindikoglu AL. Ligandrol (LGD-4033)-Induced Liver Injury. ACG Case Rep J. 2020. https://doi.org/10.14309/crj.0000000000000370
Wallstab F, et al. Ligandrol-induced liver injury – Case Report. Z Gastroenterol. 2023;61(5):522–525. https://doi.org/10.1055/a-1886-4666
Morimoto M, Yamaoka M, Hara T. A selective androgen receptor modulator SARM-2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys. Pharmacol Res Perspect. 2020;8:e00563. https://doi.org/10.1002/prp2.563
FDA (2017): “FDA In Brief: FDA warns against using SARMs in body-building products” (safety + enforcement context).
FDA: Warning letters / enforcement actions (searchable database; many letters cite SARMs as unapproved drugs / illegal in supplements).
Health Canada: recalls/advisories database (search “SARM”, “ostarine”, “LGD-4033”, etc.).
Therapeutic Goods Administration (TGA): safety alerts / warnings about SARMs (and related “sports supplements” risks).
World Anti-Doping Agency (WADA): Prohibited List (SARMs are prohibited under anabolic agents).
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