Long-term persistence of Chikungunya virus neutralizing antibodies in human populations of North Eastern Thailand

Long-term persistence of Chikungunya virus neutralizing antibodies in human populations of North Eastern Thailand

Virology Journal 2014, 11:183  doi:10.1186/1743-422X-11-183 http://www.virologyj.com/content/11/1/183

Narong Nitatpattana, Kobkan Kanjanopas, Sutee Yoksan, Wichai Satimai, Narong Vongba, Sasiporn Langdatsuwan, Khajornpong Nakgoi, Supot Ratchakum, Nadia Wauquier, Marc Souris, Prasert Auewarakul and Jean-Paul Gonzalez

Chikungunya virus (CHIKV) outbreak recurrences in Thailand are unpredictable and separated by unexplained and often long silent epidemiological periods that can last for several years. These silent periods could be explained in part by the fact that infection with one CHIKV strain confers lasting natural immunity, even against other CHIKV strains. In this study we evaluated the persistence of CHIKV-specific neutralizing antibodies in the population of Chumpae District, Khon Kaen Province, nineteen years after a CHIKV outbreak occurred in the same area in 1991. Read More…

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